Error in DESeqDataSet(se, design = design, ignoreRank) : some values in assay are negative

The original code:
DDS & lt; -deseqdatasetfrommatrix (countData = exprSet,
colData = colData,
design = ~ group_list)
Reason for error: Negative value -1 in exprSet
Correction: Replace the value of -1 in the matrix
exprSet[exprSet==-1] < 0


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