The solution

hystrix:
  command:
    default:
      execution:
        isolation:
          thread:
            timeoutInMilliseconds: 60000 

ribbon:  
  ReadTimeout: 60000  
  ConnectTimeout: 60000  

zuul:
  host: 
    connect-timeout-millis: 10000
    socket-timeout-millis: 60000

Depending on the situation, it might be the Ribbon, or you don’t need to set the ribbon

2018-01-30 10:27:43.315 WARN  [http-nio-9999-exec-1] [hio-gateway] o.s.c.n.z.f.post.SendErrorFilter - Error during filtering
com.netflix.zuul.exception.ZuulException: Forwarding error
    at org.springframework.cloud.netflix.zuul.filters.route.RibbonRoutingFilter.handleException(RibbonRoutingFilter.java:170)
    at org.springframework.cloud.netflix.zuul.filters.route.RibbonRoutingFilter.forward(RibbonRoutingFilter.java:145)
    at org.springframework.cloud.netflix.zuul.filters.route.RibbonRoutingFilter.run(RibbonRoutingFilter.java:88)
    at com.netflix.zuul.ZuulFilter.runFilter(ZuulFilter.java:112)
    at com.netflix.zuul.FilterProcessor.processZuulFilter(FilterProcessor.java:193)
    at com.netflix.zuul.FilterProcessor.runFilters(FilterProcessor.java:157)
    at com.netflix.zuul.FilterProcessor.route(FilterProcessor.java:118)
    at com.netflix.zuul.ZuulRunner.route(ZuulRunner.java:96)
    at com.netflix.zuul.http.ZuulServlet.route(ZuulServlet.java:116)
    at com.netflix.zuul.http.ZuulServlet.service(ZuulServlet.java:81)
    at org.springframework.web.servlet.mvc.ServletWrappingController.handleRequestInternal(ServletWrappingController.java:157)
    at org.springframework.cloud.netflix.zuul.web.ZuulController.handleRequest(ZuulController.java:44)
    at org.springframework.web.servlet.mvc.SimpleControllerHandlerAdapter.handle(SimpleControllerHandlerAdapter.java:50)
    at org.springframework.web.servlet.DispatcherServlet.doDispatch(DispatcherServlet.java:963)
    at org.springframework.web.servlet.DispatcherServlet.doService(DispatcherServlet.java:897)
    at org.springframework.web.servlet.FrameworkServlet.processRequest(FrameworkServlet.java:970)
    at org.springframework.web.servlet.FrameworkServlet.doPost(FrameworkServlet.java:872)
    at javax.servlet.http.HttpServlet.service(HttpServlet.java:648)
    at org.springframework.web.servlet.FrameworkServlet.service(FrameworkServlet.java:846)
    at javax.servlet.http.HttpServlet.service(HttpServlet.java:729)
    at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:230)
    at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:165)
    at org.apache.tomcat.websocket.server.WsFilter.doFilter(WsFilter.java:52)
    at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:192)
    at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:165)
    at org.springframework.boot.web.filter.ApplicationContextHeaderFilter.doFilterInternal(ApplicationContextHeaderFilter.java:55)
    at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107)
    at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:192)
    at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:165)
    at org.springframework.web.filter.CorsFilter.doFilterInternal(CorsFilter.java:96)
    at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107)
    at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:192)
    at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:165)
    at org.springframework.boot.actuate.trace.WebRequestTraceFilter.doFilterInternal(WebRequestTraceFilter.java:105)
    at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107)
    at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:192)
    at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:165)
    at org.springframework.web.filter.RequestContextFilter.doFilterInternal(RequestContextFilter.java:99)
    at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107)
    at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:192)
    at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:165)
    at org.springframework.web.filter.HttpPutFormContentFilter.doFilterInternal(HttpPutFormContentFilter.java:89)
    at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107)
    at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:192)
    at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:165)
    at org.springframework.web.filter.HiddenHttpMethodFilter.doFilterInternal(HiddenHttpMethodFilter.java:77)
    at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107)
    at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:192)
    at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:165)
    at org.springframework.cloud.sleuth.instrument.web.TraceFilter.doFilter(TraceFilter.java:150)
    at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:192)
    at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:165)
    at org.springframework.web.filter.CharacterEncodingFilter.doFilterInternal(CharacterEncodingFilter.java:197)
    at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107)
    at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:192)
    at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:165)
    at org.springframework.boot.actuate.autoconfigure.MetricsFilter.doFilterInternal(MetricsFilter.java:107)
    at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107)
    at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:192)
    at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:165)
    at org.apache.catalina.core.StandardWrapperValve.invoke(StandardWrapperValve.java:198)
    at org.apache.catalina.core.StandardContextValve.invoke(StandardContextValve.java:108)
    at org.apache.catalina.authenticator.AuthenticatorBase.invoke(AuthenticatorBase.java:472)
    at org.apache.catalina.core.StandardHostValve.invoke(StandardHostValve.java:140)
    at org.apache.catalina.valves.ErrorReportValve.invoke(ErrorReportValve.java:79)
    at org.apache.catalina.core.StandardEngineValve.invoke(StandardEngineValve.java:87)
    at org.apache.catalina.connector.CoyoteAdapter.service(CoyoteAdapter.java:349)
    at org.apache.coyote.http11.Http11Processor.service(Http11Processor.java:784)
    at org.apache.coyote.AbstractProcessorLight.process(AbstractProcessorLight.java:66)
    at org.apache.coyote.AbstractProtocol$ConnectionHandler.process(AbstractProtocol.java:802)
    at org.apache.tomcat.util.net.NioEndpoint$SocketProcessor.doRun(NioEndpoint.java:1410)
    at org.apache.tomcat.util.net.SocketProcessorBase.run(SocketProcessorBase.java:49)
    at java.util.concurrent.ThreadPoolExecutor.runWorker(ThreadPoolExecutor.java:1149)
    at java.util.concurrent.ThreadPoolExecutor$Worker.run(ThreadPoolExecutor.java:624)
    at org.apache.tomcat.util.threads.TaskThread$WrappingRunnable.run(TaskThread.java:61)
    at java.lang.Thread.run(Thread.java:748)
Caused by: com.netflix.client.ClientException: null
    at com.netflix.client.AbstractLoadBalancerAwareClient.executeWithLoadBalancer(AbstractLoadBalancerAwareClient.java:123)
    at com.netflix.client.AbstractLoadBalancerAwareClient.executeWithLoadBalancer(AbstractLoadBalancerAwareClient.java:81)
    at org.springframework.cloud.netflix.zuul.filters.route.support.AbstractRibbonCommand.run(AbstractRibbonCommand.java:96)
    at org.springframework.cloud.netflix.zuul.filters.route.support.AbstractRibbonCommand.run(AbstractRibbonCommand.java:42)
    at com.netflix.hystrix.HystrixCommand$2.call(HystrixCommand.java:301)
    at com.netflix.hystrix.HystrixCommand$2.call(HystrixCommand.java:297)
    at rx.internal.operators.OnSubscribeDefer.call(OnSubscribeDefer.java:46)
    at rx.internal.operators.OnSubscribeDefer.call(OnSubscribeDefer.java:35)
    at rx.internal.operators.OnSubscribeLift.call(OnSubscribeLift.java:48)
    at rx.internal.operators.OnSubscribeLift.call(OnSubscribeLift.java:30)
    at rx.internal.operators.OnSubscribeLift.call(OnSubscribeLift.java:48)
    at rx.internal.operators.OnSubscribeLift.call(OnSubscribeLift.java:30)
    at rx.internal.operators.OnSubscribeLift.call(OnSubscribeLift.java:48)
    at rx.internal.operators.OnSubscribeLift.call(OnSubscribeLift.java:30)
    at rx.Observable.unsafeSubscribe(Observable.java:10211)
    at rx.internal.operators.OnSubscribeDefer.call(OnSubscribeDefer.java:51)
    at rx.internal.operators.OnSubscribeDefer.call(OnSubscribeDefer.java:35)
    at rx.internal.operators.OnSubscribeLift.call(OnSubscribeLift.java:48)
    at rx.internal.operators.OnSubscribeLift.call(OnSubscribeLift.java:30)
    at rx.Observable.unsafeSubscribe(Observable.java:10211)
    at rx.internal.operators.OnSubscribeDoOnEach.call(OnSubscribeDoOnEach.java:41)
    at rx.internal.operators.OnSubscribeDoOnEach.call(OnSubscribeDoOnEach.java:30)
    at rx.Observable.unsafeSubscribe(Observable.java:10211)
    at rx.internal.operators.OnSubscribeDoOnEach.call(OnSubscribeDoOnEach.java:41)
    at rx.internal.operators.OnSubscribeDoOnEach.call(OnSubscribeDoOnEach.java:30)
    at rx.internal.operators.OnSubscribeLift.call(OnSubscribeLift.java:48)
    at rx.internal.operators.OnSubscribeLift.call(OnSubscribeLift.java:30)
    at rx.Observable.unsafeSubscribe(Observable.java:10211)
    at rx.internal.operators.OnSubscribeDoOnEach.call(OnSubscribeDoOnEach.java:41)
    at rx.internal.operators.OnSubscribeDoOnEach.call(OnSubscribeDoOnEach.java:30)
    at rx.Observable.unsafeSubscribe(Observable.java:10211)
    at rx.internal.operators.OnSubscribeDoOnEach.call(OnSubscribeDoOnEach.java:41)
    at rx.internal.operators.OnSubscribeDoOnEach.call(OnSubscribeDoOnEach.java:30)
    at rx.Observable.unsafeSubscribe(Observable.java:10211)
    at rx.internal.operators.OnSubscribeDoOnEach.call(OnSubscribeDoOnEach.java:41)
    at rx.internal.operators.OnSubscribeDoOnEach.call(OnSubscribeDoOnEach.java:30)
    at rx.internal.operators.OnSubscribeLift.call(OnSubscribeLift.java:48)
    at rx.internal.operators.OnSubscribeLift.call(OnSubscribeLift.java:30)
    at rx.Observable.unsafeSubscribe(Observable.java:10211)
    at rx.internal.operators.OnSubscribeDefer.call(OnSubscribeDefer.java:51)
    at rx.internal.operators.OnSubscribeDefer.call(OnSubscribeDefer.java:35)
    at rx.Observable.unsafeSubscribe(Observable.java:10211)
    at rx.internal.operators.OnSubscribeMap.call(OnSubscribeMap.java:48)
    at rx.internal.operators.OnSubscribeMap.call(OnSubscribeMap.java:33)
    at rx.Observable.unsafeSubscribe(Observable.java:10211)
    at rx.internal.operators.OnSubscribeDoOnEach.call(OnSubscribeDoOnEach.java:41)
    at rx.internal.operators.OnSubscribeDoOnEach.call(OnSubscribeDoOnEach.java:30)
    at rx.internal.operators.OnSubscribeLift.call(OnSubscribeLift.java:48)
    at rx.internal.operators.OnSubscribeLift.call(OnSubscribeLift.java:30)
    at rx.Observable.unsafeSubscribe(Observable.java:10211)
    at rx.internal.operators.OnSubscribeDoOnEach.call(OnSubscribeDoOnEach.java:41)
    at rx.internal.operators.OnSubscribeDoOnEach.call(OnSubscribeDoOnEach.java:30)
    at rx.Observable.unsafeSubscribe(Observable.java:10211)
    at rx.internal.operators.OnSubscribeDefer.call(OnSubscribeDefer.java:51)
    at rx.internal.operators.OnSubscribeDefer.call(OnSubscribeDefer.java:35)
    at rx.internal.operators.OnSubscribeLift.call(OnSubscribeLift.java:48)
    at rx.internal.operators.OnSubscribeLift.call(OnSubscribeLift.java:30)
    at rx.Observable.subscribe(Observable.java:10307)
    at rx.Observable.subscribe(Observable.java:10274)
    at rx.internal.operators.BlockingOperatorToFuture.toFuture(BlockingOperatorToFuture.java:51)
    at rx.observables.BlockingObservable.toFuture(BlockingObservable.java:412)
    at com.netflix.hystrix.HystrixCommand.queue(HystrixCommand.java:377)
    at com.netflix.hystrix.HystrixCommand.execute(HystrixCommand.java:343)
    at org.springframework.cloud.netflix.zuul.filters.route.RibbonRoutingFilter.forward(RibbonRoutingFilter.java:139)
    ... 74 common frames omitted
Caused by: java.lang.RuntimeException: java.net.SocketTimeoutException: Read timed out
    at rx.exceptions.Exceptions.propagate(Exceptions.java:58)
    at rx.observables.BlockingObservable.blockForSingle(BlockingObservable.java:465)
    at rx.observables.BlockingObservable.single(BlockingObservable.java:342)
    at com.netflix.client.AbstractLoadBalancerAwareClient.executeWithLoadBalancer(AbstractLoadBalancerAwareClient.java:102)
    ... 137 common frames omitted
Caused by: java.net.SocketTimeoutException: Read timed out
    at java.net.SocketInputStream.socketRead0(Native Method)
    at java.net.SocketInputStream.socketRead(SocketInputStream.java:116)
    at java.net.SocketInputStream.read(SocketInputStream.java:171)
    at java.net.SocketInputStream.read(SocketInputStream.java:141)
    at org.apache.http.impl.io.SessionInputBufferImpl.streamRead(SessionInputBufferImpl.java:137)
    at org.apache.http.impl.io.SessionInputBufferImpl.fillBuffer(SessionInputBufferImpl.java:153)
    at org.apache.http.impl.io.SessionInputBufferImpl.readLine(SessionInputBufferImpl.java:282)
    at org.apache.http.impl.conn.DefaultHttpResponseParser.parseHead(DefaultHttpResponseParser.java:140)
    at org.apache.http.impl.conn.DefaultHttpResponseParser.parseHead(DefaultHttpResponseParser.java:57)
    at org.apache.http.impl.io.AbstractMessageParser.parse(AbstractMessageParser.java:259)
    at org.apache.http.impl.DefaultBHttpClientConnection.receiveResponseHeader(DefaultBHttpClientConnection.java:163)
    at org.apache.http.impl.conn.CPoolProxy.receiveResponseHeader(CPoolProxy.java:167)
    at org.apache.http.protocol.HttpRequestExecutor.doReceiveResponse(HttpRequestExecutor.java:273)
    at org.apache.http.protocol.HttpRequestExecutor.execute(HttpRequestExecutor.java:125)
    at org.apache.http.impl.execchain.MainClientExec.execute(MainClientExec.java:271)
    at org.apache.http.impl.execchain.ProtocolExec.execute(ProtocolExec.java:184)
    at org.apache.http.impl.execchain.RetryExec.execute(RetryExec.java:88)
    at org.apache.http.impl.execchain.RedirectExec.execute(RedirectExec.java:110)
    at org.apache.http.impl.client.InternalHttpClient.doExecute(InternalHttpClient.java:184)
    at org.apache.http.impl.client.CloseableHttpClient.execute(CloseableHttpClient.java:82)
    at org.apache.http.impl.client.CloseableHttpClient.execute(CloseableHttpClient.java:107)
    at org.apache.http.impl.client.CloseableHttpClient.execute(CloseableHttpClient.java:55)
    at org.springframework.cloud.netflix.ribbon.apache.RetryableRibbonLoadBalancingHttpClient$1.doWithRetry(RetryableRibbonLoadBalancingHttpClient.java:94)
    at org.springframework.cloud.netflix.ribbon.apache.RetryableRibbonLoadBalancingHttpClient$1.doWithRetry(RetryableRibbonLoadBalancingHttpClient.java:72)
    at org.springframework.retry.support.RetryTemplate.doExecute(RetryTemplate.java:276)
    at org.springframework.retry.support.RetryTemplate.execute(RetryTemplate.java:157)
    at org.springframework.cloud.netflix.ribbon.apache.RetryableRibbonLoadBalancingHttpClient.executeWithRetry(RetryableRibbonLoadBalancingHttpClient.java:107)
    at org.springframework.cloud.netflix.ribbon.apache.RetryableRibbonLoadBalancingHttpClient.execute(RetryableRibbonLoadBalancingHttpClient.java:72)
    at org.springframework.cloud.netflix.ribbon.apache.RetryableRibbonLoadBalancingHttpClient.execute(RetryableRibbonLoadBalancingHttpClient.java:52)
    at com.netflix.client.AbstractLoadBalancerAwareClient$1.call(AbstractLoadBalancerAwareClient.java:109)
    at com.netflix.loadbalancer.reactive.LoadBalancerCommand$3$1.call(LoadBalancerCommand.java:303)
    at com.netflix.loadbalancer.reactive.LoadBalancerCommand$3$1.call(LoadBalancerCommand.java:287)
    at rx.internal.util.ScalarSynchronousObservable$3.call(ScalarSynchronousObservable.java:231)
    at rx.internal.util.ScalarSynchronousObservable$3.call(ScalarSynchronousObservable.java:228)
    at rx.Observable.unsafeSubscribe(Observable.java:10211)
    at rx.internal.operators.OnSubscribeConcatMap$ConcatMapSubscriber.drain(OnSubscribeConcatMap.java:286)
    at rx.internal.operators.OnSubscribeConcatMap$ConcatMapSubscriber.onNext(OnSubscribeConcatMap.java:144)
    at com.netflix.loadbalancer.reactive.LoadBalancerCommand$1.call(LoadBalancerCommand.java:185)
    at com.netflix.loadbalancer.reactive.LoadBalancerCommand$1.call(LoadBalancerCommand.java:180)
    at rx.Observable.unsafeSubscribe(Observable.java:10211)
    at rx.internal.operators.OnSubscribeConcatMap.call(OnSubscribeConcatMap.java:94)
    at rx.internal.operators.OnSubscribeConcatMap.call(OnSubscribeConcatMap.java:42)
    at rx.internal.operators.OnSubscribeLift.call(OnSubscribeLift.java:48)
    at rx.internal.operators.OnSubscribeLift.call(OnSubscribeLift.java:30)
    at rx.internal.operators.OnSubscribeLift.call(OnSubscribeLift.java:48)
    at rx.internal.operators.OnSubscribeLift.call(OnSubscribeLift.java:30)
    at rx.Observable.subscribe(Observable.java:10307)
    at rx.Observable.subscribe(Observable.java:10274)
    at rx.observables.BlockingObservable.blockForSingle(BlockingObservable.java:445)
    ... 139 common frames omitted