Panda was unable to open the. Xlsx file, xlrd.biffh.XLRDError : Excel xlsx file; not supported

The reason is that XLRD was recently updated to version 2.0.1 and only supports.xls files. So Pandas. Read_Excel (‘ xxx.xlsx ‘) will return an error.
You can install an older version of XLRD and run it in CMD:
PIP uninstall XLRD
PIP install XLRD ==1.2.0
You can also open the.xlsx file with OpenPyXL instead of XLRD:
Df = pandas read_excel (‘ data. XLSX, engine = ‘openpyxl)


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